摘要
目的 探讨发生急性胆结石胆囊炎时存在肝功能损伤接受手术治疗的具体情况。方法 选取200例2020年3月-2021年3月在本院接受治疗的急性结石性胆囊炎患者进行研究，均发生肝功能损伤，按照炎症程度将其分成三组，即轻度组（78例）、中度组（69例）、重度组（53例），分析三组的肝功能指标。结果 三组患者中，重度组的IL-8、IL-6、CRP水平高于中度组，而中度组高于轻度组；相较于轻度组与中度组，重度组的AST、TBIL、ALT水平均较高，ALB水平较低，而中度组的AST、TBIL、ALT水平较轻度组高，ALB水平较轻度组低（P＜0.05）。结论 以手术的方式治疗急性结石性胆囊炎并发肝功能损害能够获得较好的疗效，并且能够促进患者肝功能恢复。
关键词： 急性胆结石胆囊炎；并发肝功能损害；手术；临床效果
Abstract
Objective: To investigate the specific situation of surgical treatment of liver function injury in patients with acute cholecystolithiasis and cholecystitis. Methods: 200 patients with acute calculous cholecystitis who were treated in our hospital from March 2020 to March 2021 were selected for study. All patients suffered from liver function injury. They were divided into three groups according to the degree of inflammation, namely, mild group (78 cases), moderate group (69 cases), and severe group (53 cases). The liver function indexes of the three groups were analyzed. Results: The levels of IL-8, IL-6 and CRP in severe group were higher than those in moderate group, while those in moderate group were higher than those in mild group; Compared with the mild group and the moderate group, the levels of AST, TBIL, ALT in the severe group were higher and the levels of ALB were lower, while the levels of AST, TBIL, ALT in the moderate group were higher and the levels of ALB in the mild group were lower (P<0.05). The total effective rate of the three groups was 95.50%. Conclusion : Surgical treatment of acute calculous cholecystitis complicated with liver function damage can achieve good results, and can promote the recovery of liver function.
Key words： Acute gallstone cholecystitis; Complicated with liver function damage; operation; Clinical effect
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