Effect of glucosamine hydrochloride capsule on knee osteoarthritis
盐酸氨基葡萄糖胶囊治疗膝骨性关节炎的效果

摘要

目的 分析膝骨性关节炎行 盐酸氨基葡萄糖胶囊治疗的效果。方法 本次抽取104例膝骨性关节炎患者进行研究分析，病例选取时间为2021年6月-2022年6月，采取随机抽签模式均分2组，将施行尼美舒利+奥美拉唑治疗的52例患者设为参考组，在上述基础上行 盐酸氨基葡萄糖胶囊治疗的52例患者设为实验组。比较2组治疗效果。结果 治疗有效率方面实验组高（P＜0.05）。膝关节功能评分中2组治疗前比较差异不明显，无法满足统计学含义（P＞0.05）。治疗后实验组高（P＜0.05）。组内治疗后与治疗前比较有明显增加，差异有统计学含义（P＜0.05）。不良反应发生率中，实验组5.77%，参考组19.23%，可见实验组较低（P＜0.05）。结论 膝骨性关节炎行 盐酸氨基葡萄糖胶囊治疗的效果确切，可促进患者治疗效果，改善其膝关节功能，且具有较高的治疗安全性。此种治疗可于临床上推广。

Abstract

Objective To analyze the effect of glucosamine hydrochloride capsule on knee osteoarthritis.
Methods 104 patients with knee osteoarthritis were selected for research and analysis. The selected cases were from June 2021 to June 2022. They were randomly divided into two groups. 52 patients who were treated with nimesulide+omeprazole were set as the reference group, and 52 patients who were treated with glucosamine hydrochloride capsules on the above basis were set as the experimental group. The therapeutic effects of the two groups were compared.
Results The effective rate of the experimental group was high (P<0.05). In the knee joint function score, there was no significant difference between the two groups before treatment, which could not meet the statistical significance (P>0.05). After treatment, it was higher in the experimental group (P<0.05). There was a significant increase after treatment in the group compared with that before treatment, and the difference was statistically significant (P<0.05). The incidence of adverse reactions was 5.77% in the experimental group and 19.23% in the reference group, which showed that the experimental group was relatively low (P<0.05).
Conclusion   Glucosamine hydrochloride capsule is effective in the treatment of knee osteoarthritis, which can promote the therapeutic effect of patients, improve their knee joint function, and has high therapeutic safety. This kind of treatment can be popularized in clinic.